Depression is one of the most widespread health conditions in the world. According to the World Health Organization, it affects more than 280 million people globally, cutting across age, gender, and geography. For some, depression is a temporary episode linked to a major life event. For others, it is a chronic condition that flares and recedes across a lifetime. Despite its prevalence, depression remains deeply misunderstood. People still hear dismissive phrases like “just snap out of it,” or “try to be positive.” Yet modern neuroscience and decades of clinical research show that depression is rooted in complex interactions between brain chemistry, genetics, environment, and psychology.
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